Dr. Cooper is assuming the role of Chair of the UCI Department of Pediatrics (effective August 2011) and is PI of the UCI Institute for Clinical and Translational Science. He is an NIH funded nationally known child health researcher; has trained more than 35 pediatrician-scientists and PhDs, and led UCIs efforts first to create its first General Clinical Research Center and subsequently its successful application for a CTSA in 2009. Dr. Cooper is active in the CHOC Pediatric Pulmonary Clinic and is Board-Certified in Pediatrics and in Pediatric Pulmonology. Dr. Cooper’s role as PI of the UCI CTSA provides distinct advantages to the planned SoCal DRC. First, Dr. Cooper is privy to and involved in the latest profound changes in the NIH associated with NIH Director Dr. Francis Collins’ new vision for the link between basic science and therapeutic applications embodied in his plans for the National Center for the Advancement of Translational Science (NCATS). Second, Dr. Cooper is an active, standing member of the CTSA Consortium Key Function Committee–Child Health Oversight Committee (CC-CHOC). Representing all 60 CTSAs, CC-CHOC has developed a robust vision for pediatric research that emphasizes the need to improve the training of the next generation of pediatric health care researchers. From 1995 through 1999, Dr. Cooper was a member of the Respiratory and Applied Physiology NIH Study Section and serves regularly as an ad hoc member of several NIH study sections. His research group has focused on the mechanisms that link physical activity with the process of growth and development in healthy children and in children with disease and disability. The context of this research is uniquely suited to the goals of translational science imbedded in this DRC proposal. His group is actively investigating the molecular mechanisms that govern the inflammatory genomic and epigenetic response to exercise in leukocytes; has created the first animal model of exercise-induced bronchoconstriction; and he recently led the UCI site of the seven-center NIDDK Project HEALTHY. HEALTHY tested a school-based intervention program designed to enhance physical activity, nutrition, and health behaviors to prevent obesity and risk for type 2 diabetes in lower SES, predominately minority schools at seven sites throughout the country. The results of this study were recently published in the New England Journal of Medicine.
Dr. Clayman is world renowned for his expertise in minimally invasive surgery for kidney stone disease, kidney cancer, and strictures of the ureter and is named as one of America’s Best Doctors. Following his general surgery and urology training at the University of Minnesota, he spent two years at Southwestern Medical School in Dallas pursuing his interests in renal cancer research, kidney stone disease, and minimally invasive urology. Dr. Clayman spent 17 years at Washington University School of Medicine in St. Louis, rising to the positions of Professor of Urology and Radiology, Director of the Midwest Stone Institute, and Co-director of the Division of Minimally Invasive Surgery. In January 2002, he was appointed chair of the newly formed Department of Urology at UCI Medical Center. Dr. Clayman and his associates performed the world’s first laparoscopic removal of a kidney for benign disease and for cancer, as well as the first laparoscopic removal of a kidney and ureter to treat cancer. He helped develop a balloon catheter to treat obstruction of the ureter and performed pioneering work on percutaneous and endoscopic therapy for ureteral and kidney stones. Dr. Clayman established the first fellowship program in minimally invasive urology, and trainees of his program now occupy academic positions at universities throughout the United States, Canada, and Israel. Dr. Clayman is the author of textbooks on laparoscopic and percutaneous urologic surgery, and has published more than 480 peer-reviewed papers and book chapters. He is co-founder and coeditor of the Journal of Endourology. He has 16, minimally invasive surgical instrumentation patents to his name. He is a member of the American Board of Urology, a position he will hold through 2011. He is a member of the American Association of Genitourinary Surgeons, the Clinical Society, and the American Surgical Association.
Dr. Clayman’s patient care, teaching, and research efforts are focused on developing and perfecting all aspects of less invasive surgery in which incisions are either reduced in size or eliminated all together. In order to accomplish this goal, he and his team continue to explore a broad range of minimally invasive and noninvasive surgical techniques to bring up-to-the-moment technology into the operating room. He was named interim Dean of the School of Medicine in 2009 and was appointed to that position full time in 2010; accordingly his clinical practice and his research activities have been significantly curtailed. He currently has limited his practice to urolithiasis and image guided needle ablative cryotherapy of renal cancer.
Dr. Gregory W. Auner is a Strauss/TEAMS (Technology and Engineering Applications in Medicine and Surgery) Endowed Chair and Professor of Electrical and Computer Engineering, Biomedical Engineering, Material Science, and faculty in the Department of Surgery at Wayne State University in Detroit, MI. He is the founder and director of the Smart Sensors and Integrated Microsystems (SSIM) program at WSU. He has developed an array of instruments, sensors and microsystems for federal institutions, research institutions, and industry. Approximately 80% of his research involves the research and development of Energy Devices, DoD and Homeland Security Sensors, biomedical microsystems and BioMEMS systems. Dr. Auner has formed a consortium within the Smart Sensors Program involving the Karmanos Cancer Institute (Ultrasonic Breast Cancer Detection System) and Children’s Hospital of Michigan (Robotic Surgery and Real-Time Surgical Diagnostics). His SSIM program, along with the Chiefs of Surgery at the Wayne State University School of Medicine, Detroit Medical Center, Karmanos Cancer Institute, Children’s Hospital of Michigan, Beaumont, Oakwood and Henry Ford Hospital Systems have created the technology and engineering applications in medicine and surgery (TEAMS) which is integrating state of the art science and technology into the field of medicine. He has over 30 patents (issued and pending) in the last several years for chemical, biomedical, and environmental sensors and microsystems and over 226 peer reviewed publications.
Dr. Anthony C. Chang completed his undergraduate education with Bachelor of Arts in Molecular Biology at Johns Hopkins University (honors) and his Doctor of Medicine education at Georgetown University School of Medicine. He then completed his pediatric residency at National Children’s Hospital Medical Center and went on to his pediatric cardiology fellowship at Children’s Hospital of Philadelphia.
He was appointed a staff cardiologist at Boston Children’s Hospital with a position in the cardiac intensive care unit and later promoted to assistant professor at Harvard School of Medicine. He was later the medical director of the cardiac intensive care programs at Children’s Hospitals of Los Angeles and Miami Children’s Hospital. He is also formerly the medical director of pediatric cardiac intensive care service and chief of critical care cardiology at Texas Children’s Hospital and a tenured associate professor at Baylor College of Medicine. He is now the director of the Heart Institute at the Children’s Hospital of Orange County and division chief of the division of cardiology.
He has a Masters in Business Administration (MBA)(in Health Care Administration) degree from the University of Miami and graduated with the McGaw Award for academic excellence. In addition, he has a Masters in Public Health (MPH)(in Health Care Policy) degree from University of California at Los Angeles and graduated with the Dean’s Award for academic excellence. He is enrolled in the Masters in Biomedical Informatics (MS-BMI) program at Stanford University at present.
He is the chief editor of the textbook Pediatric Cardiac Intensive Care and the past president-elect of the Pediatric Cardiac Intensive Care Society (PCICS). He is the chief editor of the textbook Heart Failure in Children and Young Adults. He is an associate editor of Pediatric Critical Care Medicine and is on the editorial board of Cardiology in the Young and Congenital Heart Today. He is a regular reviewer for Circulation, Pediatric Critical Care Medicine, Critical Care Medicine, and numerous other journals. He publishes and lectures widely on topics in pediatric cardiac intensive care, heart failure, sudden cardiac death, adult congenital heart disease, and other aspects of congenital heart disease and has been program directors for numerous large international conferences and symposia.
He is a member of the grant review committee for pediatric research at the National Institute of Health. He is also on the board of directors for the American Heart Association. He has been on the faculty of University of California at Los Angeles School of Public Health (eMPH program) and has taught global health at the eMPH program of the University of California at Los Angeles (UCLA). He also teaches pediatric cardiology to cardiology fellows and holds a volunteer faculty appointment at the School of Medicine at University of California at Los Angeles (UCLA). He will be teaching biomedical informatics at the University of California at Los Angeles (UCLA) Anderson School of Business and School of Nursing in the Spring of 2012.
He leads pediatric heart teams all over the world and recently mainly to Asia. He was one of the founding members of the Asia-Pacific Pediatric Cardiac Society (APPCS) and will be initiating the foundation arm of the society at the bequest of the board. He has been voted “Physician of Excellence” by the Orange County Medical Association and also selected as one of America’s “Top Doctors”, “Top Pediatricians”, and “Best Cardiologists” by several organizations.